Bonn 2025 – scientific programme
Parts | Days | Selection | Search | Updates | Downloads | Help
MO: Fachverband Molekülphysik
MO 23: Cluster and Nanoparticles I (joint session MO/A)
MO 23.4: Talk
Thursday, March 13, 2025, 12:00–12:15, HS XV
Cryo-cooled beams of "small" macromolecules — •Jingxuan He1,2,3, Lena Worbs1,2, Surya Kiran Peravali1,4, Armando D. Estillore1, Amit K. Samanta1,3, and Jochen Küpper1,2,3 — 1Center for Free-Electron Laser Science (CFEL), Deutsches Elektronen-Synchrotron DESY, Hamburg, Germany — 2Department of Physics, Universität Hamburg, Germany — 3Center for Ultrafast Imaging (CUI), Universität Hamburg, Germany — 4Fakultät für Maschinenbau, Helmut-Schmidt-Universität,Germany
We demonstrated the preparation of cold and controlled beams of nanoparticles and macromolecules that are desired for x-ray single-particle-diffractive imaging (SPI) using the buffer-gas-cell (BGC) cooling and aerodynamic focusing techniques [1,2]. The cooling and control techniques we developed for SPI can be extended to experiments to study the electron dynamics in complex biomolecules on the few-femtosecond timescale [3]. Such ultrafast charge- and energy-transfer dynamics following electronic excitation were not revealed so far [4].
We present an approach toward investigating the time-resolved ultrafast dynamics in cryo-cooled proteins [1] induced by ultrashort UV/VIS pulses and advanced detection method including velocity-map-imaging using Timepix3 cameras [5].
[1] A.K. Samanta, et al., Struct. Dyn. 7, 024304 (2020)
[2] S.K. Peravali, et al., Comput. Fluids 279, 106346 (2024)
[3] M. Hervé, et al., Commun. Chem. 4, 124, (2021)
[4] H. Duan, et al., PNAS 114, 8493 (2017)
[5] H. Bromberger, et al., J. Phys. B 55, 144001 (2022)
Keywords: Single particle imaging; Buffer gas cell; aerodynamic lens; ultrafast dynamics; mass spectrometry