Bereiche | Tage | Auswahl | Suche | Aktualisierungen | Downloads | Hilfe

ST: Fachverband Strahlen- und Medizinphysik

ST 6: Medical Imaging and Treatment Monitoring

ST 6.1: Vortrag

Donnerstag, 3. April 2025, 11:00–11:15, ZHG003

Spatially resolved mid-IR spectroscopy on healthy and cancerous lung tissue — •Maximilian Schmock¹, Tobias Steinle¹, Cleo-Aron Weis², and Harald Giessen¹ — ¹4th Physics Institute and Research Center SCoPE, Universität Stuttgart, Pfaffenwaldring 57, 70569 Stuttgart, Germany — ²Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany

Cancer diagnosis is complex and can take a long time. To support and accelerate this process, the possibilities of mid-IR spectroscopy are investigated. Therefore, a widely tunable IR-laser (from 1.3 to 20 μm) is used to perform sweep-measurements on histological samples of human lung tissue. In combination with a x-y-stage, spatially resolved measurements are performed as well. We demonstrate that with this setup, different spectral features can be highlighted depending on the wavelength, with a spatial resolution of around 20 μm. For this task, the entire spectrum between 2.7 μm and 12 μm can be used. A standardized control system that controls the entire experiment allows for fast switching between different measurement types and direct feedback on the recorded data.

Keywords: IR-Spectroscopy; Pathology; Cancer; Imaging