Bereiche | Tage | Auswahl | Suche | Aktualisierungen | Downloads | Hilfe

ST: Fachverband Strahlen- und Medizinphysik

ST 7: Poster Session

ST 7.2: Poster

Donnerstag, 3. April 2025, 13:45–15:45, ZHG Foyer 1. OG

The influence of tumor tissue vascularization on temperature in Magnetic Hyperthermia — •Viorica-Monica Moisiuc and Iordana Astefanoaei — Faculty of Physics, Alexandru Ioan Cuza University of Iasi, Romania

Magnetic hyperthermia is an innovative and promising method in cancer treatment, based on the ability of magnetic nanoparticles to generate heat under the influence of a high-frequency electromagnetic field, aiming to destroy cancer cells by locally increasing the temperature [1, 2]. This work investigates the impact of tumor vascularity on the thermal heating process in therapy, considering that the structure and density of blood vessels in the tumor can significantly influence nanoparticle distribution and, therefore, the uniformity of temperature distribution in the tissue. A model has been developed to allow a detailed analysis of heat transfer in vascularized tumor tissue, taking into account the magnetic field parameters and the properties of the magnetic systems used. The study highlights the potential of magnetic hyperthermia to generate optimal therapeutic temperatures and contribute to the selective destruction of tumor tissues, emphasizing the advantages of this method in oncological therapy through its ability to provide more precise control over thermal effects on the target tissue.

Keywords: magnetic hyperthermia; nanoparticles