Regensburg 2025 – scientific programme

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BP: Fachverband Biologische Physik

BP 14: Poster Session I

BP 14.10: Poster

Tuesday, March 18, 2025, 10:00–12:30, P3

Boundary integral method for elastic solids in Stokes flow and applications in real-time deformability cytometry — •Thomas Mayr and Stephan Gekle — Universität Bayreuth, Deutschland

A Newtonian fluid at small Reynolds numbers can be described using the Stokes equation. A common choice to solve the Stokes equation numerically is the boundary integral method. Previously, this method was mainly used to describe rigid particles or capsules with an elastic membrane such as red blood cells. Here a technique is presented how to extend the boundary integral method to elastic solids discretized by the finite element method. This can be used as simple model to describe the stiffness of cells with a nucleus and a cytoskeleton, e.g. in some deformation experiments. In our case we will compare the simulations with an experimental technique called real-time deformability cytometry (RT-DC).

Keywords: boundary integral method; finite element method; microfluidics; RT-DC; cell mechanics