Regensburg 2025 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 14: Poster Session I

BP 14.3: Poster

Dienstag, 18. März 2025, 10:00–12:30, P3

Growth and characterization of MoS2 nanowalls on Ti-based bone implants — •Rania Ennaciri, Axel Printschler, Christof Neumann, and Andrey Turchanin — Friedrich Schiller University Jena, Institute of Physical Chemistry, Lessingstraße 10, 07743 Jena, Germany

Antibiotic resistance presents an important issue in the medicine field particularly in the context of bone replacement surgeries, where infections from antibiotic-resistant bacteria can lead to severe health complications and even fatalities. While titanium (Ti) is the conventional choice for bone implants, there is a clear need for further improvements of this material to enhance its antimicrobial resistance. In this regard, hybrids based two-dimensional (2D) materials, such as molybdenum disulfide (MoS2), present a great promise due to their intrinsic antimicrobial activity and biocompatibility. These properties are generally manifested through biochemical reactions, by the generation of reactive oxygen species (ROS) that can lead to the damage of bacteria DNA, proteins and lipids. Also, mechanical actions, where the sharp edges of the nanowalls can cut the bacteria wall can lead to its death. To investigate these mechanisms, we use metal-organic chemical vapor deposition (MOCVD) technique to grow different morphologies and sizes of MoS2 nanowalls on Ti implants. We use scanning electron microscope (SEM), Raman spectroscopy and X-ray electron microscopy (XPS) to characterize the structural and chemical properties and to correlate them prospectively with the antimicrobial properties as well as with the growth bone cells.