Regensburg 2025 – scientific programme

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BP: Fachverband Biologische Physik

BP 17: Poster Session II

BP 17.15: Poster

Tuesday, March 18, 2025, 18:00–20:30, P4

Subcellular distribution of green-emitting carbon nanodots — •Mariell Gassen, Mine Polat, Carla Sprengel, and Thomas Heinzel — Condensed Matter Physics Laboratory, Heinrich Heine University, Düsseldorf, Germany

Carbon nanodots are promising fluorescent nanoparticles for biomedical imaging applications and drug delivery. They frequently show fluorescence in the blue range, which causes interference with the autofluorescence of the cell [1]. To circumvent this, we produced green-emitting carbon nanodots and incubated them in cells. We report tests about their subcellular distribution and studies of their suitability as carriers for active substances.

[1] S. Fasbender et al. The Low Toxicity of Graphene Quantum Dots is Reflected by Marginal Gene Expression Changes of Primary Human Hematopoietic Stem Cells. Sci Rep 9, 12028 (2019).

Keywords: drug delivery; fluorescence; nanoparticles