Regensburg 2025 – scientific programme

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BP: Fachverband Biologische Physik

BP 18: Tissue Mechanics

BP 18.1: Invited Talk

Wednesday, March 19, 2025, 09:30–10:00, H44

Mechanical Imprints of Cell Competition — •Benoit Ladoux — Institut Jacques Monod, Université Paris Cité & CNRS

Epithelial tissues are dynamic communities of cells characterized by close intercellular communication and highly coordinated motion. The mechanical properties of these tissues are crucial for understanding key biological processes, such as homeostasis, morphogenesis, and metastasis, and are tightly regulated through cell-cell interactions. In this presentation, I will explore the role of mechanical forces in cell competition - a process where the expansion of one cell population drives the elimination of another. I will demonstrate how intercellular force transmission governs this competitive interaction, shedding light on the interplay between mechanics and cellular mechanisms.