Regensburg 2025 – scientific programme

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BP: Fachverband Biologische Physik

BP 20: Statistical Physics of Biological Systems I (joint session BP/DY)

BP 20.9: Talk

Wednesday, March 19, 2025, 17:30–17:45, H44

Slimming down through frustration — •Martin Lenz — Université Paris-Saclay, CNRS, LPTMS, 91405, Orsay, France — PMMH, CNRS, ESPCI Paris, PSL University, Sorbonne Université, Université Paris-Cité, F-75005, Paris, France

In many disease, proteins aggregate into fibers. Why? One could think of molecular reasons, but here we try something more general. We propose that when particles with complex shapes aggregate, geometrical frustration builds up and fibers generically appear. Such a rule could be very useful in designing artificial self-assembling systems.

Keywords: Self-assembly; Protein aggregation; Soft Matter; Theoretical Biophysics