Regensburg 2025 – scientific programme

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BP: Fachverband Biologische Physik

BP 30: Protein Structure and Dynamics

BP 30.4: Talk

Thursday, March 20, 2025, 15:45–16:00, H46

Sequence specificity and polymer physics — •Martin Girard — Max-Planck Institute for Polymer Research, Mainz, Germany

Sequence properties of disordered proteins in the context of phase separation has led to development of molecular grammar. So far, this has led to the development of empirical parameters tied to protein sequences.

Using surrogate models for low-complexity sequences, I will show that sequence-property relations are tied to the polymer collapse transition. I will further discuss implications for biological systems.

Keywords: Polymer physics; Disordered proteins