Regensburg 2010 – wissenschaftliches Programm
Bereiche | Tage | Auswahl | Suche | Downloads | Hilfe
BP: Fachverband Biologische Physik
BP 21: Neurobiophysics and Sensory Transduction
BP 21.5: Vortrag
Mittwoch, 24. März 2010, 15:15–15:30, H43
When less is more: Spike Sequence Processing in Neurons with Adaptive Synapses — •Hinrich Kielblock1 and Marc Timme1,2 — 1Network Dynamics Group, Max Planck Institute for Dynamics and Self-Organization, Göttingen, Germany — 2Bernstein Center for Computational Neuroscience Göttingen, Germany
The input-output relation of a neuron centrally underlies the computational capabilities of neural circuits. The response of a neuron to incoming spike signals strongly depends on the relative timing of the presynaptic spikes. For example, if the input's timing is highly regular, an increase in excitatory input can lead to a decrease of the neurons firing rate. This counterintuitive phenomenon occurs in various neural systems but its underlying mechanism is still unclear.
Here we investigate single neuron systems where a neuron receives precisely timed spiking input via one depressive synapse. Our analysis reveals that and how non-monotonic input-output relations are created by a spike timing-dependent transmission efficiency.